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Last Updated: Nov 18, 2006 - 12:32:53 PM |
Latest Research
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Psychiatry
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Substance Abuse
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Opiates
Broken Heart Syndrome can result from opioid withdrawal
People who experience abrupt withdrawal from high-dose opioids or use cocaine increase their risk of cardiac event, according to two new studies published in the June issue of Mayo Clinic Proceedings.
Jun 22, 2006 - 5:05:00 PM
Latest Research
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Psychiatry
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Substance Abuse
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Opiates
Factors influencing transition to injecting drug use among heroin users
In a study reported in the current issue of the Journal of Acquired Immune Deficiency Syndromes, scientists from the National Development and Research Institutes, Inc. (NDRI) report on a study of street-recruited heroin users in New York City, who were not injecting, to determine the incidence and predictors of making a transition to injecting. Dr. Alan Neaigus and his colleagues examined the relationship of social network influence and current individual susceptibility on this transition.
May 7, 2006 - 3:58:00 PM
Latest Research
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Psychiatry
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Substance Abuse
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Opiates
Study supports a flexible approach to methadone dosing
Methadone has been used for more than 30 years as a treatment for heroin addicts. Doctors have all along struggled to find the best doses to help patients overcome their heroin cravings without getting them used to higher levels of methadone (itself an dependence-forming substance) than necessary. A new study by Jodie Trafton and colleagues (from the VA Palo Alto Health Care System) provides strong support for the notion that there is no one dose that fits all.
Feb 13, 2006 - 5:17:00 AM
Latest Research
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Psychiatry
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Substance Abuse
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Opiates
Buprenorphine more effective in teen heroin addiction treatment retention
In a comparison of two drugs prescribed to treat teenagers dependent on heroin and other opioids, the drug buprenorphine was more effective, especially in treatment retention, according to a study in the October issue of the Archives of General Psychiatry, one of the JAMA/Archives journals.
Oct 6, 2005 - 9:00:00 PM
Latest Research
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Psychiatry
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Substance Abuse
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Opiates
Morphine leave animals more vulnerable to stress
A new study has found that opiate drugs such as morphine leave animals more vulnerable to stress. This means that stress and opiates are in a vicious cycle: Not only does stress trigger drug use, but in return the drug leaves animals more vulnerable to stress. The study, conducted at the University of New South Wales, helps to explain why people who use opiates such as heroin have very high rates of anxiety problems, including post-traumatic stress disorder, even after they stop using. That emotional fragility can also make them more likely to start using again.
Aug 29, 2005 - 10:46:00 PM
Latest Research
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Psychiatry
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Substance Abuse
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Opiates
Opiate cocktail may spare cells from morphine's dark side
Although morphine is well known as a highly effective analgesic, its clinical utility is severely limited by the development of drug tolerance, the requirement for increasing doses to maintain analgesic effect, and the development of physical dependence. In the June 7 issue of Current Biology, researchers report a new study showing that the administration of a drug cocktail containing morphine along with small doses of two versions of methadone, a related opioid drug, significantly reduced both tolerance and dependence in test animals.
Jun 7, 2005 - 1:49:00 AM
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