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Last Updated: Nov 18, 2006 - 12:32:53 PM |
Latest Research
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Pharmacology
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Antivirals
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Bavituximab
Phase Ib Trial Is Evaluating Bavituximab Administered With Common Chemotherapy Regimens
Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHM), a clinical stage biopharmaceutical company developing targeted therapeutics for the treatment of cancer and hepatitis C virus (HCV) infection, today announced initiation of patient treatment in its Phase lb clinical trial to evaluate its lead anti-phospholipid immunotherapy agent bavituximab given in combination with common cancer chemotherapy agents. The trial is expected to enroll up to 12 patients at three clinical sites in India.
Nov 17, 2006 - 10:32:00 PM
Latest Research
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Gynaecology
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Menstruation Disturbances
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Menopause
Treatment with hormones improves visual memory of postmenopausal women
Many women experience declines in their memory during and after menopause, a change thought to be due, in part, to the rapid hormonal changes they weather during that time. Now, research from the University of Michigan Health System suggests that hormone therapy might help women retain certain memory functions. In a study in the new issue of The Journal of Clinical Endocrinology & Metabolism, they report that a group of postmenopausal women showed more brain activity during a visual memory test than did women who were not taking the hormone therapy.
Nov 17, 2006 - 1:38:00 PM
Latest Research
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Psychiatry
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Forensic Psychiatry
Sleep Apnea Treatment Curbs Aggression in Sex Offenders
Obstructive sleep apnea (OSA) affects up to 20% of men in western cultures, 5% of whom experience significant physical symptoms. A study published in Journal of Forensic Sciences finds that sex offenders who suffer from OSA experience more harmful psychological symptoms than do sex offenders with normal sleep patterns.
Nov 17, 2006 - 1:36:00 PM
Latest Research
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Aging
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Dementia
Occupational therapy improves quality of life for dementia patients
Occupational therapy can help to improve the ability of people with dementia to perform daily activities and can also reduce the pressure on their caregivers, says a BMJ study published today.
Nov 17, 2006 - 1:34:00 PM
Latest Research
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Cancer
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Lung
Gene Expression Profiling Not Quite Perfected in Predicting Lung Cancer Prognosis
While there have been significant advances in the use of gene expression profiling to assess a cancer prognosis, a Mayo Clinic review and analysis of existing lung cancer studies shows that this technology has not yet surpassed the accuracy of conventional methods used to assess survival in lung cancer patients.
Nov 17, 2006 - 1:31:00 PM
Latest Research
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Psychiatry
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Substance Abuse
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Cocaine
Scientists design simple dipstick test for cocaine, other drugs
Researchers at the University of Illinois at Urbana-Champaign have developed a simple "dipstick" test for detecting cocaine and other drugs in saliva, urine or blood serum. The test is based upon DNA-gold nanoparticle technology, and can be packaged in user-friendly kits similar to those used for home pregnancy tests.
Nov 14, 2006 - 2:44:00 AM
Latest Research
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Gastroenterology
British scientists create artificial stomach
British scientists have created the world's first artificial stomach that may allow us to understand what happens in the gut and help develop healthier foods to manipulate the digestive process.
Nov 12, 2006 - 5:50:00 PM
Latest Research
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Immunology
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Autoimmune Diseases
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Lupus
Pregnant women with lupus are at higher risk for complications
Women with systemic lupus who become pregnant are at significantly greater risk for death or other medical complications than are pregnant women without lupus, Duke University Medical Center researchers have found in a nationwide study of more than 18 million women.
Nov 12, 2006 - 4:21:00 PM
Latest Research
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Neurosciences
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Memory
Memories: It's all in the packaging
Researchers at UC Irvine have found that how much detail one remembers of an event depends on whether a certain portion of the brain is activated to �package� the memory.
Nov 10, 2006 - 5:08:00 PM
Latest Research
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Cardiology
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CHF
Seven-point system gauges seriousness of heart failure in elderly
A simple points system may soon help guide treatment of elderly heart failure patients. Researchers at Washington University School of Medicine in St. Louis found that by counting how many of seven easy-to-obtain health factors a patient has, physicians can estimate the patient's risk of dying.
Nov 10, 2006 - 5:06:00 PM
Latest Research
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Neurosciences
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Stroke
New Effort to Treat Stroke More Effectively
Just a small fraction of patients who have a stroke receive the only drug � TPA � available to treat the condition. Now doctors and scientists at the University of Rochester Medical Center have developed a potential new treatment that will reach a milestone in the next few months, when the experimental treatment is tested for the first time in people who have suffered a stroke or �brain attack.�
Nov 7, 2006 - 10:24:00 PM
Latest Research
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Infectious Diseases
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AIDS
Keeping A3G in action represents a new way to attack HIV
For years researchers have been trying to understand how a few HIV-infected patients naturally defeat a virus that otherwise overwhelms the immune system. Last year, a research team at the University of Rochester Medical Center confirmed that such patients, called long-term non-progressors, maintain higher than normal levels of the enzyme called APOBEC-3G (A3G) in their white blood cells, which function to stave off infections. Now, the same group has teamed up with a structural biologist to provide the first look at the A3G structure. Such information represents an early step toward the design of a new class of drugs that could afford to all the same natural protection enjoyed by few, according to a study published today in The Journal of Biological Chemistry.
Nov 7, 2006 - 10:20:00 PM
Latest Research
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Infectious Diseases
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AIDS
Fighting HIV With HIV Virus Itself
Researchers at the University of Pennsylvania School of Medicine report the first clinical test of a new gene therapy based on a disabled AIDS virus carrying genetic material that inhibits HIV replication. For the first application of the new vector five subjects with chronic HIV infection who had failed to respond to at least two antiretroviral regimens were given a single infusion of their own immune cells that had been genetically modified for HIV resistance.
Nov 7, 2006 - 10:12:00 PM
Latest Research
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Metabolism
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Obesity
Children�s Belly Fat Increases More Than 65 Percent
Abdominal obesity increased more than 65 percent among boys and almost 70 percent among girls between 1988 and 2004. The finding of growing girth is significant because abdominal obesity has emerged as a better predictor of cardiovascular disease and type 2 diabetes risk than the more commonly used Body Mass Index, a weight to height ratio that can sometimes be misleading.
Nov 7, 2006 - 10:10:00 PM
Latest Research
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Dental
Common Antacids Could Help Keep Gingivitis at Bay
Chemicals commonly used to treat heartburn also display fighting power against the oral bacteria linked with gum disease, according to researchers at the University of Rochester Medical Center and G�teborg University in Sweden.
Nov 7, 2006 - 10:07:00 PM
Latest Research
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Radiology
New way of tracking muscle damage from radiation
Magnetic resonance imaging (MRI) could become a valuable tool for predicting the risk of muscle injury during and following radiation therapy, according to investigators at St. Jude Children's Research Hospital.
Nov 7, 2006 - 2:29:00 PM
Latest Research
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Psychiatry
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Depression
New brain-chemistry differences found in depressed women
A new brain study finds major differences between women with serious depression and healthy women in a brain-chemical system that's crucial to stress and emotions.
Nov 7, 2006 - 2:26:00 PM
Latest Research
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Infectious Diseases
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Malaria
Retina can provide a very reliable way of diagnosing cerebral malaria
The eye can provide a very reliable way of diagnosing cerebral malaria, researchers in Malawi have shown. By looking at the changes to the retina, doctors are able to determine whether an unconscious child is suffering from this severe form of malaria or another, unrelated illness, leading to the most appropriate treatment.
Nov 7, 2006 - 2:23:00 PM
Latest Research
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Gynaecology
Hormone therapy does not improve quality of life for women
A postmenopausal hormone therapy trial conducted in Estonia indicates that hormone therapy does not improve women's quality of life. The group receiving hormones and the comparison group showed no differences in general quality of life. Only those women that experienced hot flashes and night-time sweating reported beneficial effects. These results were obtained from the Estonian Postmenopausal Hormone Therapy trial (EPHT) funded by the Academy of Finland and conducted under the leadership of Research Professor Elina Hemminki from the National Research and Development Centre for Welfare and Health (Stakes).
Nov 7, 2006 - 2:20:00 PM
Latest Research
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Psychiatry
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Anxiety
Anxiety sensitivity linked to future psychological disorders
People who get scared when they experience a pounding heart, sweaty palms or dizziness -- even if the cause is something as mundane as stress, exercise or caffeine -- are more likely to develop a clinical case of anxiety or panic disorder, according to a Florida State University researcher in Tallahassee, Fla.
Nov 7, 2006 - 2:18:00 PM
Latest Research
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Metabolism
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Obesity
Rising abdominal obesity among kids causes concern
Abdominal obesity increased more than 65 percent among boys and almost 70 percent among girls between 1988 and 2004. The finding of growing girth is significant because abdominal obesity has emerged as a better predictor of cardiovascular disease and type 2 diabetes risk than the more commonly used Body Mass Index, a weight to height ratio that can sometimes be misleading.
Nov 6, 2006 - 4:44:00 PM
Latest Research
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Cytology
How cells adhere so firmly to blood vessel walls
Blood is the universal means with which different types of cells are transported in our bodies. Its movement is determined by hydrodynamic forces. The cells anchor themselves to the walls of the blood vessels in the target tissue with the aid of special adhesive molecules, which are also called receptors. In many cases these receptors are grouped in the cell surface in nanometer-sized patches. The adhesion process is based on the key and lock principle: as a rule, an adhesion molecule only bonds with specific partners. This guarantees that the cells are only brought to a halt where they are to fulfill their biological function.
Nov 4, 2006 - 8:57:00 PM
Latest Research
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Paediatrics
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Neonatology
Cot death could be linked to brain defect
The Sudden Infant Death Syndrome (SIDS) or 'cot death' that kills about 300 babies a year in Britain may be linked to a defect in the brain, scientists have said.
Nov 4, 2006 - 7:24:00 PM
Latest Research
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Psychiatry
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Substance Abuse
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Smoking
C. elegans provides model for the genetics of nicotine dependence
The unassuming C. elegans nematode worm, a 1-millimeter workhorse of the genetics lab, is quite similar to human beings in its genetic susceptibility to nicotine dependence, according to University of Michigan researchers.
Nov 4, 2006 - 6:20:00 PM
Latest Research
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Aging
Resveratrol Increases Lifespan of Obese Mice
Researchers have used a single compound to increase the lifespan of obese mice, and found that the drug reversed nearly all of the changes in gene expression patterns found in mice on high calorie diets--some of which are associated with diabetes, heart disease, and other significant diseases related to obesity. The research, led by investigators at Harvard Medical School and the National Institute on Aging, is the first time that the small molecule resveratrol has been shown to offer survival benefits in a mammal. The study is reported in the November 1 advanced online edition of Nature.
Nov 3, 2006 - 4:12:00 AM
Latest Research
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Cardiology
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Hypertension
Uric acid levels closely related to hypertension in Blacks
New research shows that higher levels of uric acid are strongly associated with high blood pressure in blacks, suggesting that a simple blood test could predict risk and that treatments to lower uric acid may be a novel way to reduce hypertension-related complications in this population.
Nov 2, 2006 - 9:21:00 PM
Latest Research
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Surgery
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Transplantation
Predicting survival in liver transplant patients
A new model based on specific characteristics of the donor and the recipient may help predict survival after liver transplantation, according to a new study.
Nov 2, 2006 - 9:15:00 PM
Latest Research
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Cardiology
American College of Cardiology announces new initiative to improve safety for patients with Acute Coronary Syndromes
The American College of Cardiology Foundation's National Cardiovascular Data Registry (NCDRTM) announced today that it will launch a new initiative to improve safety and outcomes for patients with Acute Coronary Syndrome (ACS).
Nov 2, 2006 - 9:10:00 PM
Latest Research
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Pharmacology
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Antibiotics
Two-component lantibiotic with therapeutic potential discovered
The discovery and preparation of a naturally occurring antibiotic could open the door to new therapeutic drugs for treating nasty infections. The rapid spread of drug-resistant bacterial strains poses a persistent threat to human health, and requires new sources of antibiotics to treat infections. Researchers at the University of Illinois at Urbana-Champaign are tackling this problem by discovering and preparing natural antibiotics called lantibiotics.
Oct 31, 2006 - 4:13:00 PM
Latest Research
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Aging
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Dementia
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Alzheimer's
Hope remains for Alzheimer's sufferers
The National Institute of Clinical Excellence (NICE), who last week rejected appeals to allow patients with mild Alzheimer's to receive the life-changing medication donepezil (Aricept�), will hopefully re-appraise their decision in three-years time, according to neurologist Professor Robert Kerwin in an article published in the November issue of the medical journal Future Neurology.
Oct 31, 2006 - 4:08:00 PM
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