|
Last Updated: Nov 18, 2006 - 12:32:53 PM |
Latest Research
:
Haematology
:
Thalassemias
Alpha-Thalassemia and Protection from Malaria
Over the course of human history, hundreds of thousands of genetic mutations have arisen in the global population. The most harmful ones usually disappear�by affecting an individual's �fitness,� i. e., the ability to reproduce, the mutations are lost before carriers can pass them on to their children�whereas most mutations are maintained in the population in low frequencies. Some mutations, however, can give the carrier such a large survival advantage that the mutations become positively selected for, leading to their presence in high frequencies in some populations.
Apr 21, 2006 - 12:37:00 AM
Latest Research
:
Haematology
:
Thalassemias
MBD2 Protein mediates silencing of the fetal gamma-globin gene through DNA methylation
Virginia Commonwealth University Massey Cancer Center researchers have identified the role of a protein in hemoglobin gene silencing that may one day be a potential target for the treatment of genetic blood disorders like sickle-cell anemia and beta-thalassemia on the molecular level.
Apr 11, 2006 - 10:42:00 PM
<< prev
next >>
|
