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Last Updated: Nov 18, 2006 - 12:32:53 PM |
Latest Research
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Surgery
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Transplantation
Predicting survival in liver transplant patients
A new model based on specific characteristics of the donor and the recipient may help predict survival after liver transplantation, according to a new study.
Nov 2, 2006 - 9:15:00 PM
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SALT protocol improves quality of donor lungs significantly
By performing simple clinical maneuvers to improve donor lung quality as part of the San Antonio Lung Transplant (SALT) protocol, researchers significantly increased the number of available donor lungs and transplant procedures without compromising recipient pulmonary function, length of hospital stay or survival.
Sep 15, 2006 - 5:50:00 PM
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Costimulation blockade: Will this lead to rejection-free transplants?
Years ago, the idea of attaching a donor limb onto a patient's body would have been the stuff of science fiction. But to date about two-dozen people around the world have received hand transplants.
Sep 8, 2006 - 5:20:00 PM
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Hepatorenal syndrome patients best benefited by a combined liver-kidney transplant
New UCLA research shows that combined liver-kidney transplants appear to benefit patients with diseases in both organs, including patients with potentially reversible kidney failure who have been receiving dialysis for longer than two months. The Archives of Surgery will publish the findings in its August issue.
Aug 22, 2006 - 4:29:00 AM
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'Domino' transplant program makes best use of altruistic donated kidneys
A team of Johns Hopkins researchers reporting their early experiences with "domino" kidney donation suggest that wider use of this strategy could effectively double the benefit of the organs from these non-directed, altruistic living donors.
Jul 30, 2006 - 2:34:00 AM
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British doctors carry out transplant with beating heart
Doctors at a hospital have successfully transplanted a beating heart into a 58-year-old patient in the first operation of its kind in Britain. The transplant was carried out two weeks ago at Papworth Hospital in Cambridge, northeast of London. The male patient was doing 'extremely well', according to the hospital Monday.
Jun 5, 2006 - 5:09:00 PM
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Older donor hearts just as good - Research
Patients who receive healthy hearts from donors 50 years of age and older appear to fare just as well as patients who receive younger hearts, and that may be good news for potentially expanding a small donor pool, a University of Alberta study has found.
Apr 15, 2006 - 6:25:00 PM
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Another successful face transplant in China
Doctors in China have performed the country's first face transplant, and the second such operation in the world. A surgical team at the Xijing hospital in Xi'an replaced two-thirds of the face of 30-year-old Li Guoxing, who was disfigured after a bear mauled him two years ago, Zhang Yingzhi, the president of the hospital, said Friday.
Apr 15, 2006 - 6:00:00 PM
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Another Implant of Total Artificial Heart TAH-t
A cardiac surgery team at Virginia Commonwealth University�s Pauley Heart Center has performed the first artificial heart implant on the East Coast. The CardioWest temporary Total Artificial Heart, or TAH-t, is the only total artificial heart approved by the U.S. Food and Drug Administration.
Apr 5, 2006 - 2:47:00 PM
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Predicting successful outcomes in living-donor liver transplants
A new study on identifying which patients were likely to have poor outcomes following a living-donor liver transplant (LDLT) found that measuring how a certain non-toxic dye was eliminated by the liver shortly after surgery was an accurate indicator of liver function, and therefore a reliable indicator of the outcome of the procedure. The study used a simple non-invasive device to measure the dye, making it particularly useful in treating transplant patients.
Apr 5, 2006 - 1:38:00 PM
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Liver transplants from non-heart beating donors can increase organ supply
Liver transplants from non-heart beating donors have the potential to increase the supply of organs by as much as 20%, according to experts in this week�s BMJ.
Feb 17, 2006 - 7:05:00 PM
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Carbon Monoxide Protects Transplanted Kidneys In Rats
Carbon monoxide, a highly toxic gas often called the "silent killer," may prove useful for extending the life of transplanted organs, suggests a University of Pittsburgh study that found prolonged, low-dose exposure to be protective against chronic rejection in a rat kidney transplant model. Chronic rejection is the primary reason that patients require second or third transplant operations.
Jan 24, 2006 - 6:04:00 PM
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Metabolic syndrome - new risk factor for kidney-pancreas transplant patients
A three-year multi-center study of kidney-pancreas transplant recipients has identified a new risk factor for impaired kidney function, which may help physicians refine their treatment strategies.
Jan 21, 2006 - 10:08:00 PM
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Metabolic syndrome is a risk factor for long-term kidney transplant dysfunction
A three-year multi-center study of kidney-pancreas transplant recipients has identified a new risk factor for impaired kidney function, which may help physicians refine their treatment strategies.
Jan 21, 2006 - 8:47:00 PM
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Cyclosporine may play a beneficial role for patients with liver transplanted for HCV infection
Liver transplant patients with hepatitis C virus (HCV) achieved significantly better long-term viral response when taking the immunosuppressive agent Cyclosporine along with interferon-ribavirin combination therapy. Cyclosporine also showed efficacy against Hepatitis C virus in vitro.
Jan 6, 2006 - 10:48:00 PM
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Use Of Kidney Paired Donation For Incompatible Donors Could Expand Donor Pool
A preliminary study suggests that kidney paired donation transplantation, in which incompatible donor/recipient pairs exchange kidneys so that each recipient receives a compatible kidney, had graft survival rates equivalent to compatible live donor transplants, according to a study in the October 5 issue of JAMA.
Oct 6, 2005 - 8:41:00 PM
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Transplantation
Severe Hypoglycemia Rare After Islet Transplantation
Episodes of dangerously low blood glucose, or hypoglycemia, were greatly reduced in people who received an islet transplant for poorly controlled type 1 diabetes, according to an analysis of outcomes in 138 patients who had the procedure at 19 medical centers in the United States and Canada. This is one of the conclusions of the Collaborative Islet Transplant Registry (CITR), which tracks many factors affecting the success of this experimental procedure in people with severe type 1 diabetes. The CITR, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health (NIH), released its second annual report today.
Sep 8, 2005 - 1:58:00 AM
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Largest study to date in patients undergoing bone marrow transplantation
Together with 16 other institutions in the United States, University of Minnesota researchers led the largest study to date in patients with leukemia and related disorders undergoing bone marrow transplantation from unrelated donors. The study was designed to determine whether one of two general approaches to prevent graft-versus-host-disease (GVHD), a potentially lethal complication, might result in improved survival.
Aug 4, 2005 - 11:25:00 AM
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Bone loss after Liver Transplants is Preventable
A new study found that the drug used to treat osteoporosis, when used in combination with calcium and vitamin D, can prevent the additional bone loss that commonly occurs after liver transplants. The treatment also helped stabilize bone loss in patients who already had osteoporosis, and helped improve their bone mineral density (BMD).
Jul 22, 2005 - 12:46:00 AM
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Type 1 Diabetes Successfully Treated after Series of Islet Cell Transplants
A Davidson woman has been successfully treated for her Type 1 diabetes through a procedure performed at Carolinas Medical Center. Paul F. Gores, M.D., has led a multi-disciplinary team through a series of three pancreatic islet cell transplants since the summer of 2003. The result is a patient who is now insulin-free.
Jun 8, 2005 - 8:14:00 PM
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Surgery
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Survival Benefit of Aerosolized Cyclosporine in Lung Transplant Patients may be due to Patient Imbalances
A survival benefit for lung transplant patients seen with Chiron�s Pulminiq (aerosolized cyclosporine) may be due to patient imbalances across treatment groups in the drug�s pivotal study, FDA said.
Jun 4, 2005 - 11:37:00 AM
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Transplantation
Therapeutic Drug Monitoring Optimizes Efficacy of Immunosuppressive Therapy in Organ Transplants
Monitoring the level of CellCept(R)(mycophenolate mofetil) in a patient's blood in the months following an organ
transplant may enable physicians to identify the precise amount of drug needed by each patient to prevent organ rejection without increasing toxicity, thereby optimizing efficacy and tolerability of the drug over time.
May 25, 2005 - 8:59:00 PM
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Surgery
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Transplantation
Combination Therapy Shows Significant Anti-rejection Benefits in Heart Transplants
Amid the debate over which combination of immunosuppressive agents works best in helping patients fight off rejection of their new heart after transplant surgery, a new study led by researchers at the UCLA Heart Transplant Program showed that one particular combination using tacrolimus (TAC, or Prograf) had significant anti-rejection benefits for heart transplant patients over other combinations.
May 24, 2005 - 10:43:00 AM
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Everolimus Approved for Prophylaxis of Organ Rejection in Heart and Kidney Transplants
Certican (everolimus) was recently approved by Swissmedic for the prophylaxis of organ rejection in heart and kidney transplant patients. This decision not only provides access to an innovative new therapy for Swiss transplant patients, but also supports expanded regulatory submissions in Asia and Europe.
May 22, 2005 - 10:30:00 PM
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Survival Rates Better for Children Receiving Living Donor Liver Transplant
Children who undergo liver transplantation have better survival rates with living donor liver transplant graft than with deceased donor organ transplant, although factors other than the type of graft also are important, according to a study in the May issue of Archives of Surgery, one of the JAMA/Archives journals.
May 18, 2005 - 5:34:00 PM
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Surgery
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Transplantation
Risk of death from post-injury multiple organ failure decreased in last decade
Improvements in critical care and decreased use of blood transfusions over the course of the last decade are associated with decreases in the rate, severity and risk of death from post-injury multiple organ failure, according to a study in the May issue of the Archives of Surgery, one of the JAMA/Archives journals.
May 18, 2005 - 5:34:00 PM
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Surgery
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Transplantation
Animal to human transplantation � future potential, present risk
Transplantation of animal organs, living cells and tissues into humans is termed xenotransplantation. Recent experiments have shown that the transplantation of organs from genetically modified pigs into baboons can yield moderate to good results and this raises hopes for the future of organ transplantation from pigs to humans.
May 3, 2005 - 11:59:00 PM
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