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Last Updated: Nov 17th, 2006 - 22:35:04 |
Latest Research
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Infectious Diseases
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Prion Diseases
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CJD
Seven UK cases of Creutzfeldt-Jakob disease associated with transplanted human tissue
Seven cases of Creutzfeldt-Jakob disease (CJD) associated with transplanted human tissue have occurred in the UK over a period of 33 years, reveals a study published ahead of print in the Journal of Neurology Neurosurgery and Psychiatry.
Apr 20, 2006, 16:50
Latest Research
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Infectious Diseases
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Prion Diseases
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CJD
First Successful Blood Test for 'Mad Cow' Disease Prions
Researchers at the University of Texas Medical Branch at Galveston (UTMB) have found a way to detect in blood the malformed proteins that cause "mad cow disease," the first time such "prions" have been detected biochemically in blood.
Aug 29, 2005, 23:22
Latest Research
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Infectious Diseases
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Prion Diseases
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CJD
Blocking apoptosis fails to stop prion damage in mouse brains
Researchers knew that prions, the misfolded proteins that cause mad cow disease and other brain disorders, were killing off a class of important brain cells in a transgenic mouse model. But when they found a way to rescue those cells, they were astonished to discover the mice still became sick.
Dec 23, 2004, 13:07
Latest Research
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Infectious Diseases
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Prion Diseases
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CJD
Mad cow prions piggyback on iron-storing proteins after surviving digestive juices
A new study from the Department of Pathology at Case Western Reserve University School of Medicine shows that the infectious version of prion proteins, the main culprits behind the human form of mad cow disease or variant Creutzfeldt-Jakob Disease (vCJD), are not destroyed by digestive enzymes found in the stomach. Furthermore, the study finds that the infectious prion proteins, also known as prions, cross the normally stringent intestinal barrier by riding piggyback on ferritin, a protein normally absorbed by the intestine and abundantly present in a typical meat dish. The study appears in the Dec. 15 issue of the Journal of Neuroscience.
Dec 16, 2004, 18:50
Latest Research
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Infectious Diseases
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Prion Diseases
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CJD
Testing Transepithelial Prion Protein Transport In Vitro
The discovery of the "mad cow" variant of Creutzfeldt�Jakob disease (CJD) as a foodborne illness not only created a worldwide scare but also focused attention on the mechanisms of transmission of the infective agent, the scrapie prion protein (PrPSc).
Dec 15, 2004, 18:45
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