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A STAT3 Call for Regeneration
Feb 16, 2005, 15:20, Reviewed by: Dr.
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By Pankaj, US Correspondent,
Regeneration in the CNS after spinal cord injury is limited because of obstacles such as glial scars and myelin-based inhibitory factors. On the other hand, axons in the PNS are much more resilient. This week, Qiu et al. provide evidence for Janus kinase (JAK)�signal transducer and activator of transcription (STAT) signaling downstream of the cytokines. The JAK2�STAT3 pathway appears to be growth-promoting after a peripheral nerve injury. 
- Journal of Neuroscience
Society for Neuroscience
Jin Qiu, William B. J. Cafferty, Stephen B. McMahon, and Stephen W. N. Thompson
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